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PH-alternatywa dla SAA cz.2

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Doping

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Szacuny 0 Napisanych postów 12 Wiek 31 lat Na forum 10 lat Przeczytanych tematów 396
A to niski jesteś i stąd taka dobra sylwetka ;)
niech sie wypowie ktos na temat epi :)
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Szacuny 5 Napisanych postów 758 Wiek 31 lat Na forum 16 lat Przeczytanych tematów 29576
dzięki dobry pocisk nie jest zły :)

„Citus, Altius, Fortius” - „Szybciej, Wyżej, Mocniej”

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Szacuny 1 Napisanych postów 71 Wiek 39 lat Na forum 10 lat Przeczytanych tematów 3068
panowie pomożecie ? i możne wie ktoś jak z libido w trakcie cyklu ?
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Szacuny 0 Napisanych postów 12 Wiek 31 lat Na forum 10 lat Przeczytanych tematów 396
kozak gdybys mial 185/190 juz bys tak dobrze nie wygladal przy tej wadze i to nie byl pocisk
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Ekspert
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Adrianekk84
panowie pomożecie ? i możne wie ktoś jak z libido w trakcie cyklu ?

W trakcie cyklu na czym?

Diller
Co polecacie dorzucic na cyklu z EPI? czym sie odbanowac i czy dawac no boostera co trening na cyklu z EPI ii kreatyne? I jakie osłonki polecacie ;)

A to ma być pierwszy cykl? Jeśli tak to najlepiej zrób solo. Z osłonek to tylko bym dał lecytynę, garlicin i coś na stawy, np. Flexit. Na wątrobę nic nie bierz tylko po cyklu na regenerację wrzuć np. Hepatil. Kreatynę wprowadź dopiero w ostatnim tygodniu cyklu. Jako, że Epi powoduje wzrost ciśnienie to lepiej nie bierz dodatkowo żadnych supli co powodują podobne efekty.

Zmieniony przez - mdma85 w dniu 2013-08-17 19:21:55
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mdm85 Tren six z At 2 opakowania
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Wg informacji w necie powoduje czasowy spadek libido, jak również spadek wytwarzania endogennego testosteronu.

Znalazłem fajne info na temat tego PH:

Trenavar


Nomenclature:

Estra-4,9,11-triene-3,17-dione

Synonyms:

Trenavar, Trendione

History:

This is a brand new prohormone from PHF/IBE, never seen before on the prohormone or pharmaceutical market.

Function:

This is a prohormone to the veterinary drug and black-market bodybuilding steroid trenbolone. Unlike previous "tren" prohormones, this one actually converts in the body to trenbolone. Previous "tren" PHs converted to the structurally similar - but markedly weaker - steroid dienolone.

Structure:

This prohormone has the same three conjugated double bonds as trenbolone, and differs from it only in that this hormone has a 17-ketone, where trenbolone has a 17b-hydroxy function. In the body this ketone will be readily hydrolysed by 17b-hydroxysteroid dehydrogenase type 5 (17b-HSD5) into the active form, trenbolone.

Effects:

Conversion to trenbolone should be high, so effects should be identical to the injectable form - with the exception of the famed "tren cough". Whatever the explanation for "tren cough" (and many have been suggested), since it's a reaction to the sudden parenteral introduction of some compound directly into the body, it's highly unlikely that any orally administered compound will have the same effect.
Trenbolone is one of the strongest injectable steroids on the market, so effects experienced from Trenavar can be expected to be largely the same - huge strength and size increases, accelerated fat loss, and enhanced vascularity.

Side Effects:

Blood pressure is likely to be dose-dependently elevated to a significant degree, cholesterol levels and liver function markers are likely to be adversely affected, though to what extent remains to be seen. Commonly reported trenbolone sides include night-sweats, mood swings, androgenic hair loss and/or growth, temporary loss of libido, as well as the suppression of endogenous testosterone production, and it would be sensible to assume that these may also result from use of Trenavar.

Metabolism and Bioavailability:

Warning: if you're not interested in advanced steroid metabolism discussion, skip over this section. If you want solid info on how and why an oral tren PH should work, read on.

The anabolic effects of trenbolone are due in part to the enhanced androgen receptor binding that the conjugated double bond system causes [1], and also because trenbolone is an antagonist of the glucocorticoid receptor [2]. The double bonds extending up the backbone of the steroid flattens the steroid considerably, which makes it an excellent fit for the androgen receptor. It also makes the molecule much more flexible, and therefore less receptor-specific [3]. Trenbolone is incapable of being affected by 5a-reductase, 5b-reductase, or aromatase. But will it work orally?

The first place to turn to for information on steroids is the seminal 1969 work Androgens and Anabolic Agents by Julius Vida. Unfortunately this compound isn't among the 666 compounds discussed there, and there's a shortage of information on trenbolone by oral adminstration. I was fortunate enough to find a study which compared the anabolic effects of oral and subcutaneous application of trenbolone in rats [4], and the results were frankly startling. They found that to have a comparable anabolic effect, trenbolone needed to be administered orally at 100 times the dosage as when administered by subcutaneous injection (see graph). Sounds pretty bad for a tren PH then, right? Well, the good news is we're not rats.


Trenbolone is metabolised differently in different species - in rats, around 40% is excreted as a dione form, as well as several metabolites hydroxylated in various positions [5], but in man only one metabolite has been identified - the 17a-epimer [6].



The ratio of excreted trenbolone (17b-trenbolone) to epitrenbolone (17a-trenbolone) is estimated at 1:5 in a 24hr period [7].

What this means is that although Trenavar is a prohormone to trenbolone, it doesn't appear to be a significant metabolite in humans. The equilibrium of the reaction between 17-one and 17b-ol appears to be weighted heavily - in fact pretty much exclusively - in favour of the 17b-ol, so Trenavar should convert readily to the active form trenbolone. Once converted to trenbolone, it will be open to the same metabolism mechanisms as injectable tren - conversion via sulfatase to epitrenbolone and excretion as glucoronides.

Of course, this is largely conjecture, since neither trenbolone nor a precursor to it has ever been on the supplement market before... or has it?
A few years ago ALRI released an encapsulated product called "Methoxy TRN", advertised as containing "17b-methoxytrienbolone". This was quickly pulled from the shelves soon after its release, leaving only a few highly-collectable bottles and a reputation for tremendous strength and size gains and roadmap vascularity. This supplement was tested in 2008, and the researchers discovered the tell-tale mass spectra of trenbolone (and no sign of the advertised methoxy group) [8].

Detection Limits:

An anti-doping study from 1996 found that orally administered trenbolone was detectable by mass spectrometry for two to four days after a single administration, unlike injectable trenbolone, which is detectable for much longer [9]. The detection of trenbolone after administration of Trenavar is likely to follow similar lines, though detection methods may have improved since then. Athletes subjected to doping tests should of course avoid this and all other prohibited performance-enhancing products altogether.

Dosages and Cycle Durations:

Empirical evidence is the only way to determine this; once the product has been used by enough people we'll have a better idea of how much, and for how long, Trenavar is best used.

References

[1] Steroids 74 (2009) 172–197
[2] Acta Endocrinologica, Vol 110, 1 Suppla, S129-S130
[3] J Steroid Biochem 1979;13:45–59.
[4] Toxicol Sci. 2002;70:202–211.
[5] Xenobiotica. 1981 Jul;11(7):489-500.
[6] Biol. Mass Spectrom. 20 (1991) 459–466.
[7] Recent advances in doping analysis (2). (1995) 269-274.
[8] Anal Chim Acta. 2009 Apr 1;637(1-2):92-100.
[9] Recent advances in doping analysis (3). (1996) 83-94.

Zmieniony przez - mdma85 w dniu 2013-08-17 19:41:58
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treche juz wiem a jak myslisz robic na tym cykl czy lepiej to wymienic na pro halo dodam ze pierwszy cykl robiłem na pro epi
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Szacuny 11148 Napisanych postów 51566 Wiek 31 lat Na forum 24 lat Przeczytanych tematów 57816
Szczerze Ci powiem, że nie wiem Ja planuję zrobić cykl na Epi i będzie to mój pierwszy. jeśli miałbym robić kolejny to na Pro-Halo bo z tego co czytałem jest mniej toksyczny a odblok można zrobić na ogólnie dostępnych produktach.
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.

Zmieniony przez - xxKozaKxx w dniu 2013-08-17 20:15:01

„Citus, Altius, Fortius” - „Szybciej, Wyżej, Mocniej”

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