[...] examined the effect of ligand activation of PPARδ on cell growth of two human cancer cell lines, MCF7 (breast cancer) and UACC903 (melanoma) in the presence or absence of serum using two highly specific PPARδ ligands, GW0742 or cardarine (GW501516). Culturing cells in the presence of either GW0742 or GW501516 caused up-regulation of the known [...]
[...] experienced greater declines in plasma glucose and glycosylated hemoglobin. In clinical studies, Metformin, alone or in combination with a sulfonylurea, lowered mean fasting serum triglycerides, total cholesterol, and LDL cholesterol levels and had no adverse effects on other lipid levels (see Table 4). Table 4. Summary of Mean Percent Change [...]
[...] examined the effect of ligand activation of PPARδ on cell growth of two human cancer cell lines, MCF7 (breast cancer) and UACC903 (melanoma) in the presence or absence of serum using two highly specific PPARδ ligands, GW0742 or cardarine (GW501516). Culturing cells in the presence of either GW0742 or GW501516 caused up-regulation of the known [...]
A skąd wiesz ze masz nie normalne liczby? To nie takie proste. Serum IGF-I levels were significantly increased over control levels at all dosage levels by 480 min on the first day of MK-0677 administration. With repeated administration, IGF-I levels were increased up to 126% and remained elevated through 14 days, the longest treatment period [...]
A skąd wiesz ze masz nie normalne liczby? To nie takie proste. Serum IGF-I levels were significantly increased over control levels at all dosage levels by 480 min on the first day of MK-0677 administration. With repeated administration, IGF-I levels were increased up to 126% and remained elevated through 14 days, the longest treatment period [...]
A skąd wiesz ze masz nie normalne liczby? To nie takie proste. Serum IGF-I levels were significantly increased over control levels at all dosage levels by 480 min on the first day of MK-0677 administration. With repeated administration, IGF-I levels were increased up to 126% and remained elevated through 14 days, the longest treatment period [...]
[...] to the patient with hypogonadotropic hypogonadism. J Clin Endocrinol Metab 2013; 98: 1781–1788. Harman SM, Metter EJ, Tobin JD i wsp.: Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J Clin Endocrinol Metab 2001; 86: 724–731. Mulligan T, Frick MF, Zuraw QC i [...]
[...] (see Figure 1). 3.do szczurow Moreno M., Lombardi A., Lombardi P., Goglia F., Lanni A., Effects of 3,5-diiodo-L-thyronine on thyroid stimulating hormone and growth hormone serum levels in hypothyroid rats, Life Sci, 62(26); 2369-77 (1998). Abstract We have investigated the biological effects of physiological doses of 3,5-diiodo-L-thyronine [...]
[...] vivo to alter hormone metabolism and subsequent cancer risk. The objective of this study was to examine effects of dietary intake of a lignan-rich plant food (flaxseed) on serum concentrations of endogenous hormones and binding proteins (estrone, estrone sulfate, 17 beta-estradiol, sex hormone-binding globulin, progesterone, prolactin, [...]
A skąd wiesz ze masz nie normalne liczby? To nie takie proste. Serum IGF-I levels were significantly increased over control levels at all dosage levels by 480 min on the first day of MK-0677 administration. With repeated administration, IGF-I levels were increased up to 126% and remained elevated through 14 days, the longest treatment period [...]
[...] myoblasts are proliferating, differentiating and fusing to form muscle fibers. Although authors postulate that myostatin exerts its effect in an autocrine/paracrine fashion, serum myostatin has been detected demonstrating that it is also secreted into the circulation (8, 4). It is believed that the protein detected in human serum is of processed [...]
[...] with 10 microg/day 25(OH)D by mouth, starting one week prior to the first test. SUBJECTS: 24 postmenopausal women METHODS: Pharmacokinetic analysis of the increment in serum total and ionized calcium and the decrement in serum iPTH induced by an oral calcium load, based upon multiple blood samples over a 24-hour period; measurement of the [...]
[...] to assess the statistical significance of any observed differences before and after metformin. RESULTS: After metformin administration, there was a significant reduction in serum level of total testosterone (p=0.0001), free testosterone (P=0.002), and 17 hydroxyprogesterone (p=0.0001). There was also a significant increase in serum level of sex [...]
[...] mogą spowodować spadek T3, wzrost RT3, ilość tłuszczu w diecie też może mieć znaczenie, mnie ciekawi to badanie sugerujące adaptację: Alterations in basal and TRH-stimulated serum levels of thyrotropin, prolactin, and thyroid hormones in starved obese men. Carlson HE, Drenick EJ, Chopra, IJ, Hershman JM. To investigate further the alterations in [...]
[...] Elderly Men with Low or Borderline-Low Serum Testosterone Levels Benjamin Z. Leder, Jacqueline L. Rohrer, Stephen D. Rubin, Jose Gallo and Christopher Longcope As men age, serum testosterone levels decrease, a factor that may contribute to some aspects of age-related physiological deterioration. Although androgen replacement has been shown to [...]
[...] interested: Creatinine is a protein produced by muscle and released into the blood. The amount produced is relatively stable in a given person. The creatinine level in the serum is therefore determined by the rate it is being removed, which is roughly a measure of kidney function. If kidney function falls (say a kidney is removed to donate to a [...]
[...] steak. After leucine ingestion, the leucine concentration increased 7-fold; and the alpha-amino nitrogen concentration increased by 16%. Ingested leucine did not affect the serum glucose concentration. When leucine was ingested with glucose, it reduced the 2.5-hour glucose area response by 50%. Leucine, when ingested alone, increased the serum [...]
[...] However, there are other dietary factors that can affect blood lipids or the development of atherosclerosis and/or CVD. Just as the amount and type of dietary fat affects serum cholesterol, so does the amount and type of dietary carbohydrate. For example, fructose appears to have a modest LDL-C-raising effect. This may be important because [...]
[...] of thyrotropin secretion was analyzed in seven euthyroid women, before and after withdrawal of long-term thyroid hormone, by serial measurements of thyroid 131l uptake, serum thyroxine, tri-iodothyronine, and thyrotropin concentrations, and the response to thyrotropin-releasing hormone. During exogenous hormone administration, 131l uptake [...]