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Napisał(a)
Witaj, przygotowaliśmy kilka tematów które mogą Cię zainteresować:
PRZYSPIESZ SPALANIE TŁUSZCZU!
Nowa ulepszona formuła, zawierająca szereg specjalnie dobranych ekstraktów roślinnych, magnez oraz chrom oraz opatentowany związek CAPSIMAX®.
Sprawdź...
Napisał(a)
poważnie piszesz ze masz takie odczucia, czy to jakaś prowokacja?
nie spotkałem ie z takimi "reakcjami" po omega-3
nie spotkałem ie z takimi "reakcjami" po omega-3
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Napisał(a)
juz gdzies slyszalem, ze ktos popadal w stany depresyjne po zarzywaniu omegi.
ale myslalem, ze to byl gino. a tutaj chyba naprawde problem wystepuje.
Zmieniony przez - TomQ-MAG w dniu 2010-04-28 18:00:54
ale myslalem, ze to byl gino. a tutaj chyba naprawde problem wystepuje.
Zmieniony przez - TomQ-MAG w dniu 2010-04-28 18:00:54
Prowadzenie on-line, trening, dieta, suplementacja https://www.instagram.com/tomq.bb
[email protected]
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Napisał(a)
pomijam gina, ale jak ktosjest zainteresowany:
DHA enhances the noradrenaline release by SH-SY5Y cells
Purchase the full-text article
References and further reading may be available for this article. To view references and further reading you must purchase this article.
Mathieu Géraldinea, Denis Stéphaniea, Langelier Bénédictea, Denis Isabellea, Lavialle Moniquea and Vancassel SylvieCorresponding Author Contact Information, a, E-mail The Corresponding Author
a INRA, Unité de Nutrition et Régulation Lipidiques des Fonctions Cérébrales (NuRéLiCe), UR909, Domaine de Vilvert, F78352 Jouy en Josas cedex, France
Received 11 June 2009;
revised 25 August 2009;
accepted 12 September 2009.
Available online 19 September 2009.
Abstract
Polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA) and arachidonic acid (AA), are the main components of the phospholipids, in cerebral membranes. A dietary-induced cerebral DHA deficit results in altered behaviour and neurotransmission in rodents. To determine whether PUFA were acting on the neurotransmitter release machinery, we measured the release of [3H]-noradrenaline (NA) from SH-SY5Y neuroblastoma cells with modified PUFA membrane contents and from cells incubated with medium containing high DHA or AA. The membranes of cells incubated with 70 μM DHA for 3 days had 7.6-times more DHA in their ethanolamine glycerophospholipids, while the membranes of cells incubated with AA had 40% less. Incorporation of DHA enhanced basal [3H]-NA release (25%, p < 0.05), but not KCl-evoked [3H]-NA release. Brief incubation with DHA during vesicle mobilization also strongly increased [3H]-NA release. AA had no effect. The genes encoding for the calcium sensor synaptotagmin1, and for the two SNARE complex proteins syntaxin1A and synaptobrevin1 were not affected by PUFA incorporation, as indicated by assays for specific mRNAs and proteins. Thus both a high membrane DHA content and free DHA in the medium enhance the release of [3H]-NA from SH-SY5Y cells. This suggests that brain membrane DHA influences exocytosis, which then regulates neurotransmission.
I proponuje jeszcze przeczytac polski tekst:
http://www.viamedica.pl/gazety/gazeta8/darmowy_pdf.phtml?indeks=30&indeks_art=228
Zmieniony przez - faftaq w dniu 2010-04-28 19:31:55
DHA enhances the noradrenaline release by SH-SY5Y cells
Purchase the full-text article
References and further reading may be available for this article. To view references and further reading you must purchase this article.
Mathieu Géraldinea, Denis Stéphaniea, Langelier Bénédictea, Denis Isabellea, Lavialle Moniquea and Vancassel SylvieCorresponding Author Contact Information, a, E-mail The Corresponding Author
a INRA, Unité de Nutrition et Régulation Lipidiques des Fonctions Cérébrales (NuRéLiCe), UR909, Domaine de Vilvert, F78352 Jouy en Josas cedex, France
Received 11 June 2009;
revised 25 August 2009;
accepted 12 September 2009.
Available online 19 September 2009.
Abstract
Polyunsaturated fatty acids (PUFAs), particularly docosahexaenoic acid (DHA) and arachidonic acid (AA), are the main components of the phospholipids, in cerebral membranes. A dietary-induced cerebral DHA deficit results in altered behaviour and neurotransmission in rodents. To determine whether PUFA were acting on the neurotransmitter release machinery, we measured the release of [3H]-noradrenaline (NA) from SH-SY5Y neuroblastoma cells with modified PUFA membrane contents and from cells incubated with medium containing high DHA or AA. The membranes of cells incubated with 70 μM DHA for 3 days had 7.6-times more DHA in their ethanolamine glycerophospholipids, while the membranes of cells incubated with AA had 40% less. Incorporation of DHA enhanced basal [3H]-NA release (25%, p < 0.05), but not KCl-evoked [3H]-NA release. Brief incubation with DHA during vesicle mobilization also strongly increased [3H]-NA release. AA had no effect. The genes encoding for the calcium sensor synaptotagmin1, and for the two SNARE complex proteins syntaxin1A and synaptobrevin1 were not affected by PUFA incorporation, as indicated by assays for specific mRNAs and proteins. Thus both a high membrane DHA content and free DHA in the medium enhance the release of [3H]-NA from SH-SY5Y cells. This suggests that brain membrane DHA influences exocytosis, which then regulates neurotransmission.
I proponuje jeszcze przeczytac polski tekst:
http://www.viamedica.pl/gazety/gazeta8/darmowy_pdf.phtml?indeks=30&indeks_art=228
Zmieniony przez - faftaq w dniu 2010-04-28 19:31:55
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Napisał(a)
Dzieki faftaq
no jak widać u ginomena zawsze odwrotni ale juz się przyzwyczajiłem
jedyne co mogie polecic to zmiejszyć dawkę i przesunąć źródeła o-3 do ostatniego posiłku wtedy owe skutki uboczne nie będą tak uciążliwe.
no jak widać u ginomena zawsze odwrotni ale juz się przyzwyczajiłem
jedyne co mogie polecic to zmiejszyć dawkę i przesunąć źródeła o-3 do ostatniego posiłku wtedy owe skutki uboczne nie będą tak uciążliwe.
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Napisał(a)
macie jakieś tam statystyki banów ?
ginowi musicie odblokować pierworodne konto...
ginowi musicie odblokować pierworodne konto...
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