HMB badania

apokalipsa i faftaq ciekawa polemika! Moim zdaniem faftaq udowodnil nie tylko teoretycznie ale potwierdzil to faktami. IMO HMB rowniez nie ma wplywu na przyrost masy lub sily!
Pozdrawiam

ale jakimi faktami?

nie istnieją tu zasadnicze odniesienia- a więc i wnioski nie są na niczym konkretnym oparte.

Zmieniony przez - apokalipsa w dniu 2008-01-16 22:37:13

działanie hmb jeszcze potrwa kilka lat zanim wyjdzie czy działa czy nie i jak to wszystko ale......

a co do twojego pytania fat
to brałem hmb samo bez żadnych dodatków przed hmb miałem dwa cykle na krecie mono nic więcej

Faftag - badania na AWF w Warszawie i Białej Podlaskiej prowadzono na ludziach. Ostawszewski - z tego co pamiętam - też prowadził badania na ludziach. Te na karpiach to robił pod potrzeby technik hodowlanych.
Wydaje mi się, że prowadzony na tym Formu test był też dobrym "badaniem". Poprosimy Binia - podeśle trochę linków, bo ja nie mam na to czasu.
Natomiast zachęcam Cię do lektury mojego artykułu. Zapewniam wszystkich, że nikt jeszcze nie skompilował wszystkich informacji o mechanizmach działania kreatyny, argininy i hmb. Dlatego uważam te artukuły za nowatorskie i warte polecenia. Jeden z nich egzystuje nawet w tym dziale, pod tytułem: "Tajemnice kreatyny".

panie ambroziak prosze bardzo o to ten link:
https://www.sfd.pl/TAJEMNICE_KREATYNY_-_S._AMBROZIAK-t310004.html

P. Ambroziak - poczekam więc na materiały od Binia, miłoby było gdyby zechciał wkleić tutaj (bądź w moim temacie dotyczacym HMB do ktorego link dam na koncu posta) odnosniki do badan, badź ich treść. myślę, że uzupełniłoby to temat.


Tajemnice kreatyny czytałem swego czasu. Fajny art.





https://www.sfd.pl/HMB_-_wyniki_badań_dla_zainteresowanych_tematem-t376399.html

Zmieniony przez - faftaq w dniu 2008-01-18 17:35:07

panie Ambrozjaka co z tym kolesiem co brał po 20 gram hmb i pisal ze nic mu nie poszlo oprocz nadkwasoty i odwodnienia?

uff nie bylo latwo znalezc ale to chyba toto :D

Witam
jako ze Slawek obiecal wpadam tylko na chwile podrzucic garstke badan dotyczacych skutecznosci HMB

milej lektury :D - to oczywiscie punkt wyjscia
oraz prosze poczytac na koncu uwage :D


Beta-hydroxy-beta-methylbutyrate ingestion, Part I: effects on strength and fat free mass. PMID: 11128859Related Articles
Gallagher PM, Carrithers JA, Godard MP, Schulze KE, Trappe SW
Med Sci Sports Exerc, 32 (12): 2109-15, 2000
PURPOSE: The purpose of this investigation was 1) to determine whether HMB supplementation results in an increase in strength and FFM during 8 wk of resistance training and 2) determine whether a higher dose of HMB provides additional benefits. METHODS: Thirty-seven, untrained, college-aged men were assigned to one of three groups: 0, 38, or 76 mg x kg(-1) x d(-1) of HMB (approximately equal to 3 and 6 g x d(-1), respectively). Resistance training consisted of 10 different exercises performed 3 d x wk(-1) for 8 wk at 80% of 1-repetition maximum (1RM). The 1RM was reevaluated every 2 wk with workloads adjusted accordingly. RESULTS: No differences were observed in 1RM strength among the groups at any time. However, the 38 mg x kg (-1) x d(-1) group showed a greater increase in peak isometric torque than the 0 or 76 mg.kg(-1) x d(-1) groups (P < 0.05). The 76 mg x kg(-1) x d(-1) group had a greater increase in peak isokinetic torque than the 0 or 38 mg x kg(-1) x d(-1) groups at 2.1, -3.15, and -4.2 rad x s(-1) (P < 0.05). Plasma creatine phosphokinase (CPK) activity was greater for the 0 mg x kg(-1) x d(-1) versus the 38 or 76 mg x kg(-1) x d(-1) groups at 48 h after the initial training bout (P < 0.05). In addition, no differences were observed in body fat between the three groups. However, the 38 mg x kg(-1) x d(-1) group exhibited a greater increase in FFM (P < 0.05). CONCLUSIONS: Although the IRM strength gains were not significantly different, HMB supplementation appears to increase peak isometric and various isokinetic torque values, and increase FFM and decrease plasma CPK activity. Lastly, it appears that higher doses of HMB ( i.e., > 38 mg x kg(-1) x d(-1)) do not promote strength or FFM gains.


Creatine and beta-hydroxy-beta-methylbutyrate (HMB) additively increase lean body mass and muscle strength during a weight-training program. PMID: 11448573Related Articles
Jówko E, Ostaszewski P, Jank M, Sacharuk J, Zieniewicz A, Wilczak J, Nissen S
Nutrition, 17 (7-8): 558-66, 2001
We investigated whether creatine (CR) and beta-hydroxy-beta-methylbutyrate (HMB) act by similar or different mechanisms to increase lean body mass (LBM) and strength in humans undergoing progressive resistance-exercise training. In this double-blind, 3-wk study, subjects (n = 40) were randomized to placebo (PL; n = 10), CR ( 20.0 g of CR/d for 7 d followed by 10.0 g of CR/d for 14 d; n = 11), HMB (3.0 g of HMB/d; n = 9), or CR-and-HMB (CR/HMB; n = 10) treatment groups. Over 3 wk, all subjects gained LBM, which was assessed by bioelectrical impedance analysis. The CR, HMB and CR/HMB groups gained 0.92, 0.39, and 1.54 kg of LBM, respectively, over the placebo group, with a significant effect with CR supplementation (main effect P = 0.05) and a trend with HMB supplementation (main effect P = 0.08). These effects were additive because there was no interaction between CR and HMB (CR x HMB main effect P = 0.73). Across all exercises, HMB, CR, and CR/HMB supplementation caused accumulative strength increases of 37.5, 39.1, and 51.9 kg, respectively, above the placebo group. The exercise-induced rise in serum creatine phosphokinase was markedly suppressed with HMB supplementation (main effect P = 0.01). However, CR supplementation antagonized the HMB effects on serum creatine phosphokinase (CR x HMB interactive effect P = 0.04). Urine urea nitrogen and plasma urea were not affected by CR supplementation, but both decreased with HMB supplementation (HMB effect P < 0.05), suggesting a nitrogen-sparing effect. In summary, CR and HMB can increase LBM and strength, and the effects are additive. Although not definitive, these results suggest that CR and HMB act by different mechanisms.


Effect of leucine metabolite beta-hydroxy-beta-methylbutyrate on muscle metabolism during resistance-exercise training. PMID: 8941534Related Articles
Nissen S, Sharp R, Ray M, Rathmacher JA, Rice D, Fuller JC, Connelly AS, Abumrad N
J Appl Physiol, 81 (5): 2095-104, 1996
The effects of dietary supplementation with the leucine metabolite beta-hydroxy-beta-methylbutyrate (HMB) were studied in two experiments. In study 1, subjects (n = 41) were randomized among three levels of HMB supplementation (0, 1.5 or 3.0 g HMB/day) and two protein levels (normal, 117 g/day, or high, 175 g/day) and weight lifted for 1.5 h 3 days/wk for 3 wk. In study 2, subjects (n = 28) were fed either 0 or 3.0 g HMB/day and weight lifted for 2-3 h 6 days/wk for 7 wk. In study 1, HMB significantly decreased the exercise-induced rise in muscle proteolysis as measured by urine 3-methylhistidine during the first 2 wk of exercise (linear decrease, P < 0.04). Plasma creatine phosphokinase was also decreased with HMB supplementation (week 3, linear decrease, P < 0.05). Weight lifted was increased by HMB supplementation when compared with the unsupplemented subjects during each week of the study (linear increase, P < 0.02). In study 2, fat-free mass was significantly increased in HMB-supplemented subjects compared with the unsupplemented group at 2 and 4-6 wk of the study (P < 0.05). In conclusion, supplementation with either 1.5 or 3 g HMB/day can partly prevent exercise-induced proteolysis and/or muscle damage and result in larger gains in muscle function associated with resistance training.


Supplementation with beta-hydroxy-beta-methylbutyrate (HMB) and alpha-ketoisocaproic acid (KIC) reduces signs and symptoms of exercise-induced muscle damage in man. PMID: 16286672Related Articles
van Someren KA, Edwards AJ, Howatson G
Int J Sport Nutr Exerc Metab, 15 (4): 413-24, 2005
This study examined the effects of beta-hydroxyl-beta-methylbutyrate (HMB) and alpha-ketoisocaproic acid (KIC) supplementation on signs and symptoms of exercise-induced muscle damage following a single bout of eccentrically biased resistance exercise. Six non-resistance trained male subjects performed an exercise protocol designed to induce muscle damage on two separate occasions, performed on the dominant or non-dominant arm in a counter-balanced crossover design. Subjects were assigned to an HMB/KIC (3 g HMB and 0.3 g alpha-ketoisocaproic acid, daily) or placebo treatment for 14 d prior to exercise in the counter-balanced crossover design. One repetition maximum (1RM), plasma creatine kinase activity (CK), delayed onset muscle soreness (DOMS), limb girth, and range of motion (ROM) were determined pre-exercise, at 1h, 24 h, 48 h, and 72 h post-exercise. DOMS and the percentage changes in 1RM, limb girth, and ROM all changed over the 72 h period (P < 0.05). HMB//IC supplementation attenuated the CK response, the percentage decrement in 1RM, and the percentage increase in limb girth (P < 0.05). In addition, DOMS was reduced at 24 h post-exercise (P < 0.05) in the HMB/KIC treatment. In conclusion, 14 d of HMB and KIC supplementation reduced signs and symptoms of exercise-induced muscle damage in non-resistance trained males following a single bout of eccentrically biased resistance exercise.


Nutritional supplementation of the leucine metabolite beta-hydroxy-beta-methylbutyrate (hmb) PMID: during resistance training. PMID: 10978853Related Articles
Panton LB, Rathmacher JA, Baier S, Nissen S
Nutrition, 16 (9): 734-9, 2000
The effects of supplementation of the leucine metabolite beta-hydroxy-beta-methylbutyrate (HMB) were examined in a resistance training study. Thirty-nine men and 36 women between the ages of 20-40 y were randomized to either a placebo (P) supplemented or HMB supplemented ( 3.0 g HMB/d) group in two gender cohorts. All subjects trained three times per week for 4 wk. In the HMB group, plasma creatine phosphokinase levels tended to be suppressed compared to the placebo group following the 4 wk of resistance training (HMB:174. 4 +/- 26.8 to 173.5 +/- 17.0 U/L; P:155.0 +/- 20.8 to 195.2 +/- 23.5 U/L). There were no significant differences in strength gains based on prior training status or gender with HMB supplementation. The HMB group had a greater increase in upper body strength than the placebo group (HMB: 7.5 +/- 0.6 kg; P:5.2 +/- 0.6 kg; P = 0.008). The HMB groups increased fat-free weight by 1.4 +/- 0.2 kg and decreased percent fat by 1.1% +/- 0.2% while the placebo groups increased fat-free weight by 0.9 +/- 0.2 kg and decreased percent fat by 0.5% +/- 0.2% (fat-free weight P = 0.08, percent fat P = 0.08, HMB compared to placebo). In summary, this is the first short-term study to investigate the roles of gender and training status on the effects of HMB supplementation on strength and body composition. This study showed, regardless of gender or training status, HMB may increase upper body strength and minimize muscle damage when combined with an exercise program.


Effect of dietary supplements on lean mass and strength gains with resistance exercise: a meta-analysis. PMID: 12433852Related Articles
Nissen SL, Sharp RL
J Appl Physiol, 94 (2): 651-9, 2003
The purpose of this study was to quantify which dietary supplements augment lean mass and strength gains during resistance training. Peer-reviewed studies between the years 1967 and 2001 were included in the analysis if they met a predetermined set of experimental criteria, among which were at least 3-wk duration and resistance-training 2 or more times a week. Lean mass and strength were normalized for meta-analysis by conversion to percent change per week and by calculating the effect size for each variable. Of the 250 supplements examined, only 6 had more than 2 studies that met the criteria for inclusion in the meta-analysis. Creatine and beta-hydroxy-beta-methylbutyrate (HMB) were found to significantly increase net lean mass gains of 0.36 and 0.28%/wk and strength gains of 1.09 and 1.40%/wk (P < 0.05), respectively. Chromium, dehydroepiandrosterone, androstenedione, and protein did not significantly affect lean gain or strength. In conclusion, two supplements, creatine and HMB, have data supporting their use to augment lean mass and strength gains with resistance training.


Uwaga
oczywiscie nie mozna przyjac ze HMB dziala zawsze i na kazdego (jak i w kazdym badaniu :D)
jednak nie mozna mowic o tym HMB w badaniach nie potwierdza swojego dzialania

Przyczyny, dla których hmb na niektórych nie działa, wyjaśniałem niedwano w jednym z postów o hmb. Może moderatorom uda się znalesć tamtą wypowiedź, bo nie bardzo mam czas pisać to od nowa?...

poszukam