Z Linus Pauling Institute, o witaminie b6:
Toxicity
Because adverse effects have only been documented from vitamin B6 supplements and never from food sources, safety concerning only the supplemental form of vitamin B6 (pyridoxine) is discussed. Although vitamin B6 is a water-soluble vitamin and is excreted in the urine, long-term supplementation with very high doses of pyridoxine may result in painful neurological symptoms known as sensory neuropathy. Symptoms include pain and numbness of the extremities and in severe cases, difficulty walking. Sensory neuropathy typically develops at doses of pyridoxine in excess of 1,000 mg per day. However, there have been a few case reports of individuals who developed sensory neuropathies at doses of less than 500 mg daily over a period of months. Yet, none of the studies in which an objective neurological examination was performed reported evidence of sensory nerve damage at intakes below 200 mg pyridoxine daily (24). To prevent sensory neuropathy in virtually all individuals, the Food and Nutrition Board of the Institute of Medicine set the tolerable upper intake level (UL) for pyridoxine at
100 mg/day for adults (see table below) (7). Because placebo-controlled studies have generally failed to show therapeutic benefits of high doses of pyridoxine, there is little reason to exceed the UL of 100 mg/day.
Czyli jeżeli przekroczysz 1000 mg dziennie - 76 923% RDA - to spodziewaj się czegoś złego.
500 mg - istnieje jakaś tam możliwość, że tak sie stanie - jeżeli bedziesz brał tak przez kilka miesięcy (38 462% RDA)
200 mg - nie ma dowodów na to, że coś się stało na tym poziomie (15 385% RDA)
Raczej nie masz sie czego obawiać z tym 170% dziennego spożycia...
Zmieniony przez - IQB-4 w dniu 2008-06-14 00:30:35
Zmieniony przez - IQB-4 w dniu 2008-06-14 00:32:10