arginina na redukcji

warto dodac do cyklu redukcyjnego??
jak by to moglo dzialac??
pewnie jako dopal do treningu, ale raczej na katabolizm nic nie poradzi, nie??

po głowie kołacze mi się, że u szczoorkoow arginina zwiększa lipolizę w okolicy brzoosznej i utlenianie glookozy, a zmniejsza poziom leptyny, troojglicerydoow, homocysteiny i kilku rzeczy jeszcze;
ale nie dam sobie za to głowy uciąć; poza tym nie interesowałam się nigdy sooplementacją argininy pod tym kątem

Z tego co się orientuję to spadek ilości leptyny wywołuje reakcję obronną mózgu ,który odczytuje tą wiadomośc jako zagrożenie utraty zapasów (tłuszczu) i moze np. zwolnić metabolzim albo 'przeznaczać wiecej do odłożenia' w tkance tłuszczowej...

Ciekawe... eh trzeba wtedy oszikiwać mózg odpowiednimi zabiegami dietetycznymi... [SR]

Zmieniony przez - fukinhot w dniu 2006-10-23 22:48:23

czyli raczej odpada thx

to to, o czym moowiłam:


Biochemical and Molecular Actions of Nutrients
Dietary L-Arginine Supplementation Reduces Fat Mass in Zucker Diabetic
Fatty Rats1
Wenjiang J. Fu,*† Tony E. Haynes,* Ripla Kohli,* Jianbo Hu,** Wenjuan Shi,*
Thomas E. Spencer,** Raymond J. Carroll,*† Cynthia J. Meininger,‡ and Guoyao Wu* **‡2
*Faculty of Nutrition, †Department of Statistics, and **Department of Animal Science, Texas A&M University
and ‡Department of Medical Physiology, The Texas A&M University System Health Science Center,
College Station, TX 77843
ABSTRACT This study was conducted to test the hypothesis that dietary supplementation of arginine, the
physiologic precursor of nitric oxide (NO), reduces fat mass in the Zucker diabetic fatty (ZDF) rat, a genetically
obese animal model of type-II diabetes mellitus. Male ZDF rats, 9 wk old, were pair-fed Purina 5008 diet and
received drinking water containing arginine-HCl (1.51%) or alanine (2.55%, isonitrogenous control) for 10 wk.
Serum concentrations of arginine and NOx (oxidation products of NO) were 261 and 70% higher, respectively, in
arginine-supplemented rats than in control rats. The body weights of arginine-treated rats were 6, 10, and 16%
lower at wk 4, 7, and 10 after the treatment initiation, respectively, compared with control rats. Arginine supplementation
reduced the weight of abdominal (retroperitoneal) and epididymal adipose tissues (45 and 25%,
respectively) as well as serum concentrations of glucose (25%), triglycerides (23%), FFA (27%), homocysteine
(26%), dimethylarginines (18–21%), and leptin (32%). The arginine treatment enhanced NO production (71–85%),
lipolysis (22–24%), and the oxidation of glucose (34–36%) and octanoate (40–43%) in abdominal and epididymal
adipose tissues. Results of the microarray analysis indicated that arginine supplementation increased adipose
tissue expression of key genes responsible for fatty acid and glucose oxidation: NO synthase-1 (145%), heme
oxygenase-3 (789%), AMP-activated protein kinase (123%), and peroxisome proliferator-activated receptor

coactivator-1 (500%). The induction of these genes was verified by real-time RT-PCR analysis. In sum, arginine
treatment may provide a potentially novel and useful means to enhance NO synthesis and reduce fat mass in obese
subjects with type-II diabetes mellitus. J. Nutr. 135: 714–721, 2005.
KEY WORDS: ● arginine ● nitric oxide ● obesity ● diabetes ● gene

sorry za rozjazd tekstu, ale skopiowałam to od siebie z .pdf
badań na loodziach nie posiadam (chyba)

Zmieniony przez - Grasik w dniu 2006-10-23 22:56:57

podukam, podukam i przeczytam, dziękuję mocno

Dlatego tak ważne jest ciągłe mydlenie oczu temu hormonowi...

a to juz samo nie jest proste, wiec dodatkowo utrudniac arginina nie ma sensu myslalem, ze moze jakies antykatab. wlasciwosci by miala

w necie znalazłam jeszcze coś takiego:

Am J Physiol Endocrinol Metab 291: E906-E912, 2006. First published June 13, 2006;
Beneficial effects of a long-term oral L-arginine treatment added to a hypocaloric diet and exercise training program in obese, insulin-resistant type 2 diabetic patients
Pietro Lucotti,1 Emanuela Setola,1 Lucilla D. Monti,1 Elena Galluccio,2 Sabrina Costa,2 Emilia P. Sandoli,2 Isabella Fermo,3 Giovanni Rabaiotti,4 Roberto Gatti,4 and PierMarco Piatti1

1Diabetology, Endocrinology and Metabolic Disease Unit, 2Core Laboratory, Diabetology, Endocrinology and Metabolic Disease Unit, 3Separative Technics Laboratory, and 4Rehabilitation and Functional Reeducation Division, Fondazione Centro San Raffaele del Monte Tabor, Milan, Italy

Submitted 3 January 2006 ; accepted in final form 4 June 2006


Because chronic L-arginine supplementation improves insulin sensitivity and endothelial function in nonobese type 2 diabetic patients, the aim of this study was to evaluate the effects of a long-term oral L-arginine therapy on adipose fat mass (FM) and muscle free-fat mass (FFM) distribution, daily glucose levels, insulin sensitivity, endothelial function, oxidative stress, and adipokine release in obese type 2 diabetic patients with insulin resistance who were treated with a combined period of hypocaloric diet and exercise training. Thirty-three type 2 diabetic patients participated in a hypocaloric diet plus an exercise training program for 21 days. Furthermore, they were divided into two groups in randomized order: the first group was also treated with L-arginine (8.3 g/day), and the second group was treated with placebo. Although in the placebo group body weight, waist circumference, daily glucose profiles, fructosamine, insulin, and homeostasis model assessment index significantly decreased, L-arginine supplementation further decreased FM (P < 0.05) and waist circumference (P < 0.0001), preserving FFM (P < 0.03), and improved mean daily glucose profiles (P < 0.0001) and fructosamine (P < 0.03). Moreover, change in area under the curve of cGMP (second messenger of nitric oxide; P < 0.001), superoxide dismutase (index of antioxidant capacity; P < 0.01), and adiponectin levels (P < 0.02) increased, whereas basal endothelin-1 levels (P < 0.01) and leptin-to-adiponectin ratio (P < 0.05) decreased in the L-arginine group. Long-term oral L-arginine treatment resulted in an additive effect compared with a diet and exercise training program alone on glucose metabolism and insulin sensitivity. Furthermore, it improved endothelial function, oxidative stress, and adipokine release in obese type 2 diabetic patients with insulin resistance.




czyli wynika z tego, że u cookrzykoow (typ 2) arginina poprawia wrażliwość insoolinową

==============

wracając jeszcze do szczoorkoow, to należy sobie postawić pytanie, czy spadek poziomu leptyny to bezpośrednia zasłooga argininy, czy spadku tkanki tłooszczowej (bo wydaje mi się, że takie a nie inne "skrootowo-myślowe" sformoołowanie mojej pierwszej wypowiedzi mogło coś insynuuować )

pozdrawiam i dobranoc

Zmieniony przez - grasik w dniu 2006-10-24 00:53:02

Szukałem czegoś innego i przy okazji znalazłem to:
http://jn.nutrition.org/cgi/content/full/134/10/2888S 

wracając jeszcze do szczoorkoow, to należy sobie postawić pytanie, czy spadek poziomu leptyny to bezpośrednia zasłooga argininy, czy spadku tkanki tłooszczowej

jesli slowo wytluszczone to stawiam na to drugie :D