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pitbull61

Ekspert

Szacuny 774 Napisanych postów 16448 Wiek 44 lat Na forum 22 lat Przeczytanych tematów 169363

Smalex - polecam Vitex w tym temacie

Myślę, że Sławek mógłby więcej Ci coś powiedzieć na ten temat !

https://www.sfd.pl/pitbull61__DT__droga_do_startu_w_MPJiW_2020_start_masy,_str_15-t1172367-s61.html#post-19106389

Aby zwyciężać, trzeba być i lwem i lisem...

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ambroziak Farmakolog

Ekspert

Szacuny 128 Napisanych postów 9767 Wiek 3 lata Na forum 21 lat Przeczytanych tematów 23574

Kaziu, może błędem jest dodanie gestagenów do teścia i AI, bo te niby są antyestrogenami, ale nieraz - w zależności od preparatu, tkanki i sytuacji - wspomagają estrogeny i same wykazują aktywność estrogenną.

S. Ambroziak

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ambroziak Farmakolog

Ekspert

Szacuny 128 Napisanych postów 9767 Wiek 3 lata Na forum 21 lat Przeczytanych tematów 23574

Chodzi o niepokalanek... Ciekawe ziółko, ale brakuje opinii praktyków o jego skuteczności w zbijaniu prolo.

S. Ambroziak

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Dj_Smalec

Ekspert

Szacuny 115 Napisanych postów 11455 Wiek 42 lat Na forum 21 lat Przeczytanych tematów 83143

To bede pierwszy

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ambroziak Farmakolog

Ekspert

Szacuny 128 Napisanych postów 9767 Wiek 3 lata Na forum 21 lat Przeczytanych tematów 23574

Tylko zdaj relację...

S. Ambroziak

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Cobraf

Początkujący

Szacuny 10 Napisanych postów 1587 Na forum 19 lat Przeczytanych tematów 56426

ja potwierdzam działanie castagnusa

co prawda nie mam badań

ale libido i samopoczucie było na nim świetne przy 4 tab na noc (3tab to trochę za mało)

Dziennik: http://www.body-factory.pl/showthread.php?t=8401

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ambroziak Farmakolog

Ekspert

Szacuny 128 Napisanych postów 9767 Wiek 3 lata Na forum 21 lat Przeczytanych tematów 23574

No to może faktycznie brać T-100 z niepokalankiem...?

S. Ambroziak

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s.m.p.a. ODŻYWIANIE

Ekspert

Szacuny 431 Napisanych postów 56364 Wiek 37 lat Na forum 17 lat Przeczytanych tematów 184874

Sławku jak najbardziej bym próbował...
nie wczytywałem się dokładnie ale....

[The premenstrual syndrome: effectiveness of Vitex agnus castus].
[Article in German]
Döll M.
Source
[email protected]
Abstract
Premenstrual syndrome (PMS) is a complex combination of a variety of symptoms including mood swings, anxiety, depression, tender breasts and food cravings. For some women the physical pain and emotional stress are severe enough to affect their daily routines and activities. The causes of the premenstrual syndrome have not yet been understood clearly, but have been attributed to hormonal and neuronal dysbalance, diet and lifestyle. Hyperprolactinemia seems to be an important factor which is considered to be part of the endocrine disorder. Different clinical investigations and double blind trials have shown that preparations containing Vitex agnus castus fruit extract are a useful tool to decrease pathophysiologicaly increased prolactin serum levels and though could be an effective treatment for women suffering from premenstrual syndrome.

Chaste tree (Vitex agnus-castus)--pharmacology and clinical indications.
Wuttke W, Jarry H, Christoffel V, Spengler B, Seidlová-Wuttke D.
Source
Department of Clinical and Experimental Endocrinology, University of Göttingen, Germany. [email protected]
Abstract
Extracts of the fruits of chaste tree (Vitex agnus castus = AC) are widely used to treat premenstrual symptoms. Double-blind placebo-controlled studies indicate that one of the most common premenstrual symptoms, i.e. premenstrual mastodynia (mastalgia) is beneficially influenced by an AC extract. In addition, numerous less rigidly controlled studies indicate that AC extracts have also beneficial effects on other psychic and somatic symptoms of the PMS. Premenstrual mastodynia is most likely due to a latent hyperprolactinemia, i.e. patients release more than physiologic amounts of prolactin in response to stressful situations and during deep sleep phases which appear to stimulate the mammary gland. Premenstrually this unphysiological prolactin release is so high that the serum prolactin levels often approach heights which are misinterpreted as prolactinomas. Since AC extracts were shown to have beneficial effects on premenstrual mastodynia serum prolactin levels in such patients were also studied in one double-blind, placebo-controlled clinical study. Serum prolactin levels were indeed reduced in the patients treated with the extract. The search for the prolactin-suppressive principle(s) yielded a number of compounds with dopaminergic properties: they bound to recombinant DA2-receptor protein and suppressed prolactin release from cultivated lactotrophs as well as in animal experiments. The search for the chemical identity of the dopaminergic compounds resulted in isolation of a number of diterpenes of which some clerodadienols were most important for the prolactin-suppressive effects. They were almost identical in their prolactin-suppressive properties than dopamine itself. Hence, it is concluded that dopaminergic compounds present in Vitex agnus castus are clinically the important compounds which improve premenstrual mastodynia and possibly also other symptoms of the premenstrual syndrome.

The effects of a special Agnus castus extract (BP1095E1) on prolactin secretion in healthy male subjects.
Merz PG, Gorkow C, Schrödter A, Rietbrock S, Sieder C, Loew D, Dericks-Tan JS, Taubert HD.
Source
Department for Clinical Pharmacology, Frankfurt University Clinic, Neumarkt, Germany.
Abstract
The effects of three doses of a special Agnus castus extract (BP1095E1)--extracts from 120 mg, 240 mg and 480 mg of drug per day--were examined within the framework of a placebo-controlled clinical study of tolerance and prolactin secretion in 20 healthy male subjects during a period of 14 days. There was good tolerance during the study as regards the following: adverse effects, the effects on blood pressure and heart rate, blood count, Quick's test, clinical chemistry as well as testosterone, FSH and LH values. During each study phase the 24-hour prolactin secretion profile was measured from the penultimate to the final day, and the amount of prolactin release was monitored an hour after TRH stimulation on the last day. A significant increase in the 24-hour profile was registered with the lowest dose in comparison to placebo, the opposite being the case with the higher doses, i.e. a slight reduction. In contrast to the administration of placebo, the 1-hour AUC after TRH stimulation resulted in a significant increase with the lowest dose and a significant reduction with the highest dose. The results suggest effects of the special Agnus castus extract which are dependent on the dose administered and the initial level of prolactin concentration.

[Vitex agnus castus extract in the treatment of luteal phase defects due to latent hyperprolactinemia. Results of a randomized placebo-controlled double-blind study].
[Article in German]
Milewicz A, Gejdel E, Sworen H, Sienkiewicz K, Jedrzejak J, Teucher T, Schmitz H.
Source
Abteilung für Endokrinologie, Medizinische Hochschule, Hamburg.
Abstract
The efficacy of a Vitex agnus castus preparation (Strotan capsules) was investigated in a randomized double blind study vs. placebo. This clinical study involved 52 women with luteal phase defects due to latent hyperprolactinaemia. The daily dose was one capsule (20 mg) Vitex agnus castus preparation and placebo, respectively. Aim of the study was to prove whether the elevated pituitary prolactin reserve can be reduced and deficits in luteal phase length and luteal phase progesterone synthesis be normalized. Blood for hormonal analysis was taken at days 5-8 and day 20 of the menstrual cycle before and after three month of therapy. Latent hyperprolactinaemia was analysed by monitoring the prolactin release 15 and 30 min after i.v. injection of 200 micrograms TRH. 37 complete case reports (placebo: n = 20, verum: n = 17) after 3 month of therapy were statistically evaluated. The prolactin release was reduced after 3 months, shortened luteal phases were normalised and deficits in the luteal progesterone synthesis were eliminated. These changes were significant and occurred only in the verum group. All other hormonal parameters did not change with the exception of 17 beta-estradiol which rouse up in the luteal phase in patients receiving verum. Side effects were not seen, two women treated with the Vitex agnus castus preparation got pregnant. The tested preparation is thought to be an efficient medication in the treatment of luteal phase defects due to latent hyperprolactinaemia.

co prawda na szybko znalezione ale info powinno być ok :)

Zmieniony przez - s.m.p.a. w dniu 2011-09-29 08:51:36

Niedostępny do odwołania. Zdrowia dla WSZYSTKICH!

https://www.facebook.com/pages/Wszystko-Ch**/363238457019620

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pitbull61

Ekspert

Szacuny 774 Napisanych postów 16448 Wiek 44 lat Na forum 22 lat Przeczytanych tematów 169363

Brałem Vitex (niepokalanka) juz kilka razy, ostatnio w połączeniu z 6-bromo, czyli antyestrogenem i zawsze spisywał się doskonale. Myślę, że jest to bardzo dobre uzupełnienie

https://www.sfd.pl/pitbull61__DT__droga_do_startu_w_MPJiW_2020_start_masy,_str_15-t1172367-s61.html#post-19106389

Aby zwyciężać, trzeba być i lwem i lisem...

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