KUBINHO nie jestem Sławkiem, ale udało mi się coś znaleźć co może Cię zaciekawić.
"Neuropsychobiology. 2003;47(2):61-5.
Is the arginine-nitric oxide pathway involved in the pathogenesis of schizophrenia?
Yanik M, Vural H, Kocyigit A, Tutkun H, Zoroglu SS, Herken H, Savaş HA, Köylü A, Akyol O.
Department of Psychiatry, Faculty of Medicine, University of Harran, Sanliurfa, Turkey.
[email protected]
Abstract
The reciprocal regulation of arginase and nitric oxide synthase (NOS) in L-arginine-metabolizing pathways has been demonstrated. There are various evidences of the role of the nitric oxide (NO) in several neuropsychiatric disorders including schizophrenia. However, there is no study which has investigated the role of arginase as an important part of the arginine regulatory system affecting NOS activity in schizophrenia. This study aims to investigate arginase, manganese (Mn) and total nitrite levels (a metabolite of NO) and their relationship to the arginine-NO pathway in patients with schizophrenia. Arginase activities, Mn and total nitrite levels were measured in plasma from 46 patients with schizophrenia and 32 healthy control subjects. Plasma arginase activities and Mn were found to be significantly lower and total nitrite level higher in patients with schizophrenia compared with controls. Our results suggest that the arginine-NO pathway is involved in the pathogenesis of schizophrenia."
"Eur Arch Psychiatry Clin Neurosci. 2004 Feb;254(1):43-7.
The role of the arginine-nitric oxide pathway in the pathogenesis of bipolar affective disorder.
Yanik M, Vural H, Tutkun H, Zoroğlu SS, Savaş HA, Herken H,
Koçyiğit A, Keleş H, Akyol O.
Harran Universitesi, Tip Fakültesi, Araştirma Uygulama Hastanesi, 63100 Sanliurfa, Turkey.
[email protected]
Abstract
There is a reciprocal regulation of arginase and nitric oxide synthase (NOS) in L-arginine-metabolizing pathways. Nitric oxide (NO) may be involved in some psychiatric disorders like schizophrenia, depression and bipolar affective disorder (BPAD). To our knowledge, there is no study in the literature in which the role of arginase, an important part of the arginine regulatory system affecting NOS activity, was investigated in BPAD. This study aims to investigate arginase, manganese (Mn) and total nitrite levels (a metabolite of NO) and their relationship to the arginine-NO pathway in patients with BPAD. Arginase activities, Mn and total nitrite levels were measured in plasma from forty-three patients with BPAD (Type one) and thirty-one healthy control subjects. Plasma arginase activities and Mn were found to be significantly lower and total nitrite level higher in patients with BPAD compared with controls. Our results suggest that the arginine-NO pathway is involved in the pathogenesis of BPAD."
Dlatego z uwagi na chorobę kolei ja odstawiłbym osobiście suplementację argininą. Skonsultowałbym wszytskie suple brane przez niego z lekarzem który zna się na rzeczy a nie jest tylko lekarzem
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Trzeba by tu było przeanalizować dawki jakie są szkodliwe bo to także istotna kwestia.
Aha jeszcze jedno nikt nie siedzi 24 na dobę na kompie
Zmieniony przez - s.m.p.a. w dniu 2011-02-08 20:19:36