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Aspartam lub jego brak w produktach Olimpu i Biogenixa.

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ambroziak Farmakolog
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Szacuny 128 Napisanych postów 9767 Wiek 3 lata Na forum 21 lat Przeczytanych tematów 23574
Niestety... Często powtarzam: informacje internetowe nie są weryfikowane, więc trzeba mieć sporo wprawy w odpowiednim ich filtrowaniu.

S. Ambroziak

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duzo i jeszcze wiecej o aspartamie, zebrane w jednym mijescu http://dorway.com/dorwblog/ 

Niech masa bedzie z wami ....:)

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Maniek jest na krucjacie

faktycznie podobnych zrodel jest w sieci mnostwo

wszystkie w domysle wskazuja na swiatowy spisek o ile pamietam :D

cos moze byc na rzeczy
ale czy to taki diabel ?
nie wiem ... :D
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a to mi tak wpadlo przed oczy przy poszukiwaniu materialow do pracy


Artificial sweeteners and cancer risk in a network of case–control studies

S Gallus1,*, L Scotti1, E Negri1, R Talamini2, S Franceschi3, M Montella4, A Giacosa5, L Dal Maso2 and C La Vecchia1,6
1 Istituto di Ricerche Farmacologiche ‘Mario Negri’, Via Eritrea 62, 20157 Milan
2 Servizio di Epidemiologia e Biostatistica, Centro di Riferimento Oncologico, Via Pedemontana Occ.le, 33081 Aviano (Pordenone), Italy
3 International Agency for Research on Cancer, 150 Cours Albert Thomas, F-69372 cedex 08, Lyon, France
4 Unità di Epidemiologia, Istituto Tumori ‘Fondazione Pascale’, Via Mariano Semmola, 80100 Naples
5 Policlinico di Monza, Via Amati 11, 20052 Monza (MI)
6 Istituto di Statistica Medica e Biometria, Università degli Studi di Milano, Via Venezian 1, 20133 Milan, Italy

* Correspondence to: Dr S. Gallus, Istituto di Ricerche Farmacologiche ‘Mario Negri’, Via Eritrea 62, 20157 Milan, Italy. Tel: +39 02 39014 526; Fax: +39 02 33200231; E-mail: [email protected]


Abstract
Top
Abstract
introduction
materials and methods
results
discussion
Acknowledgements
References

Background: The role of sweeteners on cancer risk has been widely debated over the last few decades. To provide additional information on saccharin and other sweeteners (mainly aspartame), we considered data from a large network of case–control studies.

Methods: An integrated network of case–control studies has been conducted between 1991 and 2004 in Italy. Cases were 598 patients with incident, histologically confirmed cancers of the oral cavity and pharynx, 304 of the oesophagus, 1225 of the colon, 728 of the rectum, 460 of the larynx, 2569 of the breast, 1031 of the ovary, 1294 of the prostate and 767 of the kidney (renal cell carcinoma). Controls were 7028 patients (3301 men and 3727 women) admitted to the same hospitals as cases for acute, non-neoplastic disorders. Odds ratios (ORs), and the corresponding 95% confidence intervals (CIs), were derived by unconditional logistic regression models.

Results: The ORs for consumption of saccharin were 0.83 (95% CI 0.30–2.29) for cancers of the oral cavity and pharynx, 1.58 (95% CI 0.59–4.25) for oesophageal, 0.95 (95% CI 0.67–1.35) for colon, 0.93 (95% CI 0.60–1.45) for rectal, 1.55 (95% CI 0.76–3.16) for laryngeal, 1.01 (95% CI 0.77–1.33) for breast, 0.46 (95% CI 0.29–0.74) for ovarian, 0.91 (95% CI 0.59–1.40) for prostate and 0.79 (95% CI 0.49–1.28) for kidney cancer. The ORs for consumption of other sweeteners, mainly aspartame, were 0.77 (95% CI 0.39–1.53) for cancers of the oral cavity and pharynx, 0.77 (95% CI 0.34–1.75) for oesophageal, 0.90 (95% CI 0.70–1.16) for colon, 0.71 (95% CI 0.50–1.02) for rectal, 1.62 (95% CI 0.84–3.14) for laryngeal, 0.80 (95% CI 0.65–0.97) for breast, 0.75 (95% CI 0.56–1.00) for ovarian, 1.23 (95% CI 0.86–1.76) for prostate and 1.03 (95% CI 0.73–1.46) for kidney cancer. A significant inverse trend in risk for increasing categories of total sweeteners was found for breast and ovarian cancer, and a direct one for laryngeal cancer.

Conclusion: The present work indicates a lack of association between saccharin, aspartame and other sweeteners and the risk of several common neoplasms.

Key words: cancer, case–control study, risk factor, sweeteners
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o prosze znow cos w ten desen


Consumption of Aspartame-Containing Beverages and Incidence of Hematopoietic and Brain Malignancies
Unhee Lim1, Amy F. Subar2, Traci Mouw1, Patricia Hartge1, Lindsay M. Morton1, Rachael Stolzenberg-Solomon1, David Campbell3, Albert R. Hollenbeck4 and Arthur Schatzkin1
+ Author Affiliations

1Division of Cancer Epidemiology and Genetics, 2Division of Cancer Control and Population Sciences, National Cancer Institute, NIH, Department of Health and Human Services; 3Information Management Services, Inc., Rockville, Maryland; and 4AARP, Washington, District of Columbia
Requests for reprints:
Amy Subar, Division of Cancer Control and Population Sciences, National Cancer Institute, 6130 Executive Boulevard, EPN 4005, Rockville, MD 20852-7344. Phone: 301-594-0831; Fax: 301-435-3710. E-mail: [email protected]

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Abstract

Background: In a few animal experiments, aspartame has been linked to hematopoietic and brain cancers. Most animal studies have found no increase in the risk of these or other cancers. Data on humans are sparse for either cancer. Concern lingers regarding this widely used artificial sweetener.

Objective: We investigated prospectively whether aspartame consumption is associated with the risk of hematopoietic cancers or gliomas (malignant brain cancer).

Methods: We examined 285,079 men and 188,905 women ages 50 to 71 years in the NIH-AARP Diet and Health Study cohort. Daily aspartame intake was derived from responses to a baseline self-administered food frequency questionnaire that queried consumption of four aspartame-containing beverages (soda, fruit drinks, sweetened iced tea, and aspartame added to hot coffee and tea) during the past year. Histologically confirmed incident cancers were identified from eight state cancer registries. Multivariable-adjusted relative risks (RR) and 95% confidence intervals (CI) were estimated using Cox proportional hazards regression that adjusted for age, sex, ethnicity, body mass index, and history of diabetes.

Results: During over 5 years of follow-up (1995-2000), 1,888 hematopoietic cancers and 315 malignant gliomas were ascertained. Higher levels of aspartame intake were not associated with the risk of overall hematopoietic cancer (RR for ≥600 mg/d, 0.98; 95% CI, 0.76-1.27), glioma (RR for ≥400 mg/d, 0.73; 95% CI, 0.46-1.15; P for inverse linear trend = 0.05), or their subtypes in men and women.

Conclusions: Our findings do not support the hypothesis that aspartame increases hematopoietic or brain cancer risk. (Cancer Epidemiol Biomarkers Prev 2006;15(9):1654–9)
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ambroziak Farmakolog
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Szacuny 128 Napisanych postów 9767 Wiek 3 lata Na forum 21 lat Przeczytanych tematów 23574
Czyli - na dwoje babka wróżyła...
Za to niedawno widziałem badania, że cukier sprzyja nowotworom. Jak się nie obrócić - d...pa zawsze z tyłu.

S. Ambroziak

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No wlasnie nie bardzo na dwoje :)
badania raczej nie potwierdzaja jej megaszkodliwosci
co do cukru to nawet jedno z w/w badan wspomina ew o takim zwiazku

ale fakt jak mozna zastapic czyms o mniejszej kontrowersyjnosci :) to dlaczego tego nie robic :)
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ambroziak Farmakolog
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Zapomniałem, że "saccharin" może mieć w angielskim dwa znaczenia.

S. Ambroziak

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http://curezone.com/forums/fm.asp?i=1533841#i gość opisuje w jaki spób Aspartam szkodzi-jego mechanizm

Aspartame (Equal, Nutrasweet) is with no doubt a highly toxic substance. Aspartame is produced by linking the amino acids phenylalanine and aspartic acid with a methanol molecule. The amino acids themselves are generally not a problem. There are some people who cannot metabolize phenylalanine, and it can become toxic to these individuals. The condition is called phenylketonuria (PKU), which is why the warnings are required on all products containing aspartame. Phenylalanine can also raise blood pressure in some individuals. On the other hand it is also necessary for the formation of some very important neurotransmitters. The biggest problem with aspartame is the methanol. Methanol, also known as wood alcohol, is a very powerful neurotoxin. Methanol can cause headaches, loss of vision, seizures, mood changes, and other neurological disturbances. These are all reported side effects of aspartame as well. The methanol is released when the aspartame breaks down, which does not take much. Any heat source over I think it was 80 degrees, which includes body heat will break down aspartame releasing the methanol. Neurological damage is not the only adverse effect of methanol though. Methanol is metabolized in the body in to formic acid and formaldehyde. Formic acid is the powerful irritant causing the pain of ant bites and bee stings. In the body it can irritate the organs. Formaldehyde is one of the most powerful carcinogens (cancer causing agents) known. This is why cancer is another reported side effect of aspartame use.

Aspartame has also been shown to cause weight gain, even though it is used for diet products. It does this through a couple of mechanisms. First it stimulates a blood sugar rise, which also makes it a bad choice for diabetics. The rise in blood sugar leads to an insulin spike, which in turn leads to fat production. Aspartame also stimulates the appetite, which promotes more calorie intake. To make matters worse, aspartame makes people thirstier, so they are more likely to drink more aspartame containing drinks.

Pro-aspartame advocates try to argue that methanol is not that toxic because it is also found naturally in fruit juices. What they are not telling people is that fruit juices also contain ethanol, which is the treatment for methanol poisoning.

Niech masa bedzie z wami ....:)

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wspominal kolega o dawkach szkodliwych metanolu ?

bo cos mi sie kojarza jakies prawie kosmiczne po przeliczeniu ze szczorow ...
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