Anadrol stosowany klinicznie to zdaje sie dawki rzedu nawet 1000mg dziennie.
A tu bardzo ciekawt text.
"I share your thoughts on this. Anadrol has an acidic hydrogen in the A-ring at a vicinity that is approximate to where the acidic phenolic hydrogen of estradiol is. I suspect it is a potent estrogen agonist'
Clearly if this is the case we can only combat the estrogenic side effects of oxymetholone with estrogen receptor antagonists such as Nolvadex® or Clomid®, and not with an aromatase inhibitor. The strong anti-aromatase compounds such as Cytadren and Arimidex ® would similarly prove to be totally useless with this steroid, as aromatase is uninvolved.
Anadrol 50 ® is also a very potent androgen. This trait tends to produce many pronounced, unwanted androgenic side effects. Oil skin, acne and body/facial hair growth can be seen very quickly with this drug. Many individuals respond with severe acne, often requiring medication to keep it under control. Some of these individuals find that Accutaine works well, which is a strong prescription drug that acts on the sebaceous glands to reduce the release of oils. Those with a predisposition for male pattern baldness may want to stay away from Anadrol 5007 completely, as this is certainly a possible side effect during therapy. And while some very adventurous female athletes do experiment with this compound, it is much too androgenic to recommend. Irreversible virilization symptoms can be the result and may occur very quickly, possibly before you have a chance to take action.
It is interesting to note that Anadrol 50® does exhibit some tendency to convert to dihydrotestosterone, although this does not occur via the 5-alpha reductase enzyme (responsible for altering testosterone to form DHT) as it is already a dihydrotestosterone based steroid. Aside from the added c-17 alpha alkylation (discussed below), oxymetholone differs from DHT only by the addition of a 2-hydroxymethylene group. This grouping can be removed metabolically however, reducing oxymetholone to the potent androgen l7alpha-methyl dihydrotestosterone (mesterolone; methyldihydrotestosterone)~. There is little doubt that this biotransformation contributes at least at some level to the androgenic nature of this steroid, especially when we note that in its initial state Anadrol 50® has a notably low binding affinity for the androgen receptor. So although we have the option of using the reductase inhibitor finasteride (see: Proscar®) to reduce the androgenic nature of testosterone, it offers us no benefit with Anadrol 50® as this enzyme is not involved.
The principle drawback to Anadrol 50® is that it is a 17aipha alkylated compound. Although this design gives it the ability to withstand oral administration, it can be very stressful to the liver. Anadrol 50® is particularly dubious because we require such a high milligram amount per dosage. The difference is great when comparing it to other oral steroids like Dianabol or Winstrol®, which have the same chemical alteration. Since they have a slightly higher affinity for the androgen receptor, they are effective in much smaller doses (seen in the 5mg and 2mg tablet strengths). Anadrol 50C~ has a lower affinity, which may be why we have a 50mg tablet dosage. For comparison, taking three tablets of Anadrol 50® (150mg) is roughly the equivalent of 30 Dianabol tablets or 75 Winstrol® tablets(!). When looking at the medical requirements, the recommended dosage for all ages has been 1 - 5 mg/kg of body weight. This would give a 2201b person a dosage as high as 10 Anadrol 50® tablets (500mg) per day. There should be little wonder why when liver cancer has been linked to steroid use, Anadrol 50~ is generally the culprit. Athletes actually never need such a high dosage and will take in the range of only 1-3 tablets per day. Many happily find that one tablet is all they need for exceptional results, and avoid higher amounts. Cautious users will also limit the intake of this compound to no longer than 4-6 weeks and have their liver enzymes checked regularly with a doctor. Kidney functions may also need to be looked after during longer use, as water retention/high blood pressure can take a toll on the body. Before starting a cycle, one should know to give Anadrol 50® the respect it is due. It is a very powerful drug, but not always a friendly one.
When discontinuing Anadrol 50®, the crash can be equally powerful. To begin with, the level of water retention will quickly diminish, dropping the user's body weight dramatically. This should be expected, and not of much concern. What is of great concern is restoring endogenous testosterone production. Anadrol 50® will quickly and effectively lower natural levels during a cycle, so HCG and/or Clomid®/Nolvadex ® are a must when discontinuing a cycle.
The common practice of slowly tapering off your pill dosage is wholly ineffective at raising testosterone levels. Without ancillary drugs, a run away cortisol level will likely strip much of the muscle that was gained during the cycle. If HCG and/or Clomid®/Nolvadex® are used properly, the person should be able to maintain a considerable amount of new muscle mass. Before going off, some alternately choose to first switch over to a milder injectable like
Deca-Durabolin®. This is in an effort to harden up the new mass, and can prove to be an effective practice. Although a drop of weight due to water loss is likely when making the switch, the end result should be the retention of more (quality) muscle mass with a less pronounced crash. Remember ancillaries though, as testosterone production will not be rebounding during Deca therapy.
Anonim
wbrew opini bardzo dobry srodek
Altis
CinE
Uriel
BadMad
Bo po tym mnie bebechy rypały po metandienonie tak nie mam,a brit disp wogole nie poczulem choć koledzy chwalą hyh
